Fluoride poisoning through chronic exposure is generally associated with industry. Increased intensity of the exposure may produce respiratory distress, neurological abnormalities, gastrointestinal pain, and muscular fibrillation. Prolonged exposure over years can lead to skeletal fluorosis, a crippling disease. Acute exposure (ingestion) is manifested by symptoms of nausea, vomiting, tetanic contractions, coma, and death. In an organic state, fluoride is an essential mineral in man required for bone calcification processes.